Apexa Modi
Papers
2
Total Citations
12
H-Index
2
About
Apexa Modi is a molecular biologist and genomics researcher whose work centers on CRISPR-based functional genomics, with a particular focus on advancing the precision and efficiency of large-scale gene screening technologies. Modi's most notable contributions involve the optimization of genomewide CRISPR loss-of-function (LOF) screens, specifically through the application of AsCas12a paired with multi-guide arrays — an innovative approach designed to overcome key limitations inherent in conventional CRISPR-Cas9 library systems. By refining these screening methodologies, Modi's research enhances researchers' ability to systematically uncover novel gene functions across a wide range of physiological and pathophysiological contexts, from basic cellular biology to disease-relevant pathways. Her 2023 publication on this topic has already garnered 10 citations, reflecting rapid uptake within the genomics community, while an earlier 2022 iteration of the work contributed foundational insights that helped shape the field's evolving standards. Though early in citation trajectory, Modi's research addresses a critical bottleneck in functional genomics, and her contributions position her as an emerging voice in the development of next-generation CRISPR screening platforms with broad applications in drug target discovery and gene function characterization.
Research Focus
Key Achievements
Top Papers
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- 2