Biochemical investigations and quality control

摘要

This chapter discusses the roles of the clinical biochemistry laboratory in the diagnosis, treatment, monitoring, and prognosis of disease states. The equipment used to analyse clinical samples is often complex and large laboratories will produce many thousands of results daily. However, advances made in automation, robotics, and computing have made it possible to cope with ever-increasing workloads, even when the numbers of staff are reduced. Specialist tests are often performed on clinical samples at regional centres where the required expertise is available and to reduce duplication of expensive equipment. In contrast, point-of-care testing (POCT) is increasing and although presenting numerous benefits, it presents a new challenge to the clinical laboratory. Quality control is essential for all assays and when utilized properly gives confidence to the laboratory staff and to users of the service with regard to precision and accuracy of all the tests performed.