Cerebral oxygenation measured by near-infrared spectroscopy and jugular vein oxygen saturation during robotic-assisted laparoscopic radical prostatectomy under total intravenous anaesthesia

摘要

Background The effects of total intravenous anaesthesia (TIVA) on cerebral oxygenation in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP) have not been investigated. We examined the changes in jugular venous oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (rSO2) during RALP under TIVA. Whether rSO2 could reflect SjvO2 was also examined. Methods Forty patients (ASA 1–2) undergoing RALP were enrolled. Measurements were obtained at eight time points during the operation. Results SjvO2 did not decrease at any measurement point, whereas rSO2 fell significantly 120 min after pneumoperitoneum in a steep Trendelenburg position (p <0.01). There was a weak correlation between SjvO2 and rSO2 (Pearson correlation coefficient =0.34; p <0.01). Bland–Altman analysis showed a wide interval for the limit of agreement (47%) between the two measurements. Conclusions These findings suggested that TIVA could be safely used for RALP. It was also demonstrated that rSO2 did not accurately reflect SjvO2 during RALP. Copyright © 2014 John Wiley & Sons, Ltd.