Drug repositioning

Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data

Alexander Aliper, Sergey Plis, Artem V. Artemov, Alvaro Ulloa, Polina Mamoshina, Alex Zhavoronkov

Citations: 600 • 2016

Two approaches to discovering and developing new drugs for Chagas disease

McKerrow Jh, PS Doyle, Engel Jc, LM Podust, Sheilah A. Robertson, Rafaela Salgado Ferreira, T Saxton, Michelle R. Arkin, ID Kerr, LS Brinen, CS Craik

Citations: 173 • 2009

A Repurposing Strategy Identifies Novel Synergistic Inhibitors of <i>Plasmodium falciparum</i> Heat Shock Protein 90

Dea Shahinas, Michael N. Liang, Alessandro Datti, Dylan R. Pillai

Citations: 90 • 2010

A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

Franz Gruber, Zoe C Johnston, Christopher L. R. Barratt, Paul D. Andrews

Citations: 22 • 2020

The Impact of Artificial Intelligence on Cancer Diagnosis and Treatment: A Review

Niki Najar Najafi, Helia Hajihassani, Maryam Azimzadeh Irani

Citations: 7 • 2025

Convergence of computer-aided drug discovery and artificial intelligence: Towards next-generation therapeutics

Citations: 7 • 2025

Investigating the effect of pregabalin on neuronal development using ultrashort self-assembling peptides: Assessing 3D neuronal cultures with high throughput robotic 3D bioprinting

Walaa F. Alsanie, Sherin Abdelrahman, Majid Alhomrani, Alexander U. Valle-Pérez, Ebtisam Alosimi, Hamza Habeeballah, Heba Alkhatabi, Raed I. Felimban, Abdulhakeem S. Alamri, Abdulaziz Alsharif, Bassem M. Raafat, Yusuf S. Althobaiti, Ahmed Gaber, Charlotte A. E. Hauser

Citations: 4 • 2024

Candidate anti-herpesviral drugs; mechanisms of action and resistance

Karen K. Biron

Citations: 4 • 2007

Recent artificial intelligence methods and coronaviruses

Shafeeq Ur Rehman, Furqan Shafqat, Kamal Niaz

Citations: 3 • 2022

Designing innovative therapies for neuropathic pain: pros and cons of target‐based drug discovery

James Inglese

Citations: 2 • 2014

Chemical &amp; RNAi Screening at MSKCC: A Collaborative Platform to Discover &amp; Repurpose Drugs to Fight Disease

Bhavneet Bhinder, Christophe Antczak, David Shum, Constantin Radu, Jeni P. Mahida, Nancy Liu-Sullivan, Glorymar Ibáñez, Balajee Raja, Paul Calder, Hakim Djaballah

Citations: 2 • 2014