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About

V. Reggie Edgerton is a pioneering neuroscientist and rehabilitation researcher whose work has fundamentally advanced our understanding of spinal cord injury recovery and neuroplasticity. His research sits at the intersection of neuroscience, robotics, and rehabilitation medicine, with a particular focus on how the injured spinal cord can be retrained to restore locomotion and posture. Edgerton's most influential contribution, "Retraining the Injured Spinal Cord" (2001, 382 citations), established foundational concepts for rehabilitative strategies following spinal cord injury, revealing how remaining synapses can be functionally reorganized even after devastating supraspinal input loss. This work catalyzed an entire field of activity-based rehabilitation therapies. Building on these insights, Edgerton championed the development of robotic neurorehabilitation tools, including the innovative Pelvic Assist Manipulator (PAM) and rodent robotic steppers, enabling precise, quantifiable locomotor training. His highly cited work on robot-mediated neurorehabilitation and assist-as-needed training paradigms helped establish robotics as a credible clinical rehabilitation modality. He further explored biological repair mechanisms, including olfactory ensheathing glia for axonal regeneration. With hundreds of citations across multiple disciplines, Edgerton's legacy represents a remarkable bridge between basic neuroscience and transformative clinical application.