S. Krishnaswamy
Papers
1
Total Citations
5
H-Index
1
About
S. Krishnaswamy is a structural biologist whose research centers on the molecular mechanisms of bacterial pathogenicity and drug resistance, with a particular focus on the role of bacteriophages in horizontal gene transfer. Their work explores how phage integration and excision events can introduce novel genetic material into bacterial genomes, potentially conferring new virulence factors or antibiotic resistance traits. A key contribution is the elucidation of the crystal structure of YagE, a putative DHDPS-like protein from *Escherichia coli K12*, which provides insights into the structural biology of proteins encoded within cryptic prophage regions. While this foundational study has garnered 5 citations, it represents an important step in understanding the molecular architecture of phage-associated proteins that may influence bacterial fitness and adaptability. Krishnaswamy’s research bridges structural biology and microbial genomics, offering a molecular lens through which to view the evolutionary arms race between bacteria and their viral invaders. Their work is particularly relevant for researchers investigating the structural underpinnings of bacterial evolution and the spread of antimicrobial resistance.
Research Focus
Key Achievements
Top Papers
- 1