Ronnie O. Frederick
Papers
2
Total Citations
43
H-Index
2
About
Ronnie O. Frederick is a pioneer in high-throughput structural biology, specializing in the development of automated, robotic platforms for protein production. His key research areas include cell-free translation systems, membrane protein structural studies, and NMR-based screening. Frederick’s major contribution lies in transforming costly, low-yield protein structure determination into a rapid, scalable process. His landmark 2010 paper, “Robotic large-scale application of wheat cell-free translation to structural studies including membrane proteins” (35 citations), demonstrated how robotic automation enables efficient production of challenging membrane proteins for structural analysis. In a companion study, “Rapid, robotic, small‐scale protein production for NMR screening and structure determination” (8 citations), he addressed the bottleneck of conventional validation methods by replacing time-consuming sequential screens with a streamlined, robotic workflow. This work significantly increased the success rate of identifying viable protein targets for three-dimensional structure determination. Frederick’s innovations have accelerated the pace of structural genomics, making him a key figure in advancing automated bioproduction for drug discovery and molecular biology research.
Research Focus
Key Achievements
Top Papers
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