P O Brown
Papers
1
Total Citations
1,608
H-Index
1
About
P. O. Brown is a pioneering figure in functional genomics and molecular biology, best known for revolutionizing the study of gene expression through the development of DNA microarray technology. His landmark 1996 paper, “Parallel human genome analysis: microarray-based expression monitoring of 1000 genes,” which has garnered over 1,600 citations, introduced a high-speed robotic method for printing thousands of cDNAs onto glass slides. This innovation enabled the simultaneous, quantitative monitoring of gene expression across the human genome using a two-color fluorescence hybridization assay. Brown’s work laid the foundation for modern transcriptomics, transforming how researchers investigate complex biological systems, disease mechanisms, and drug responses. Beyond this seminal contribution, his research has profoundly impacted cancer biology, evolution, and systems biology, with his publications collectively cited tens of thousands of times. A professor at Stanford University and an investigator of the Howard Hughes Medical Institute, Brown’s visionary approach to open, large-scale data sharing and collaborative science has inspired a generation of genomic scientists.
Research Focus
Key Achievements
Top Papers
- 1Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.1,608 citations · 1996