Anwei Chai

Papers

Total Citations

1,608

H-Index

About

Dr. Anwei Chai is a pioneering figure in genomics and functional genomics, best known for foundational work in the development and application of DNA microarray technology. His landmark 1996 study, “Parallel human genome analysis: microarray-based expression monitoring of 1000 genes,” which has garnered over 1,600 citations, demonstrated the first large-scale, parallel monitoring of human gene expression using high-density cDNA microarrays. By printing 1,046 human cDNAs onto glass slides and employing a sensitive two-color hybridization assay, Chai’s team established a robust, high-throughput platform for quantitative gene expression profiling. This breakthrough enabled researchers to simultaneously monitor the expression of thousands of genes, revolutionizing the study of human biology and disease. Chai’s contributions laid the critical groundwork for modern functional genomics, directly enabling the systematic analysis of gene regulation, disease mechanisms, and drug responses. His work remains a cornerstone reference in the field, reflecting his enduring impact on how scientists explore the dynamic landscape of the human genome.