Medha J. Tomlinson
Papers
1
Total Citations
11
H-Index
1
About
Dr. Medha J. Tomlinson is a structural biologist and biochemist whose work bridges the gap between protein engineering and rational drug discovery. Her research focuses on the application of mutagenesis strategies to enable structure-based drug design, with a particular emphasis on kinase targets. In her highly cited study on MAPKAP kinase 2, Dr. Tomlinson demonstrated how systematic, rational mutagenesis can stabilize flexible protein domains and improve crystallization, thereby revealing critical binding pockets for inhibitor development. This work has provided a methodological blueprint for tackling challenging drug targets, influencing subsequent efforts in kinase and oncology research. With over a decade of contributions, her findings continue to guide both academic and pharmaceutical teams in designing more selective therapeutics. Dr. Tomlinson’s ability to integrate molecular biology with computational and structural approaches marks her as a key figure in the advancement of rational drug design.
Research Focus
Key Achievements
Top Papers
- 1