Kinase

BIRB796 Inhibits All p38 MAPK Isoforms in Vitro and in Vivo

Yvonne Kuma, Guadalupe Sabio, Jenny Bain, Natalia Shpiro, Rodolfo Márquez, Ana Cuenda

Citations: 310 • 2005

An efficient rapid system for profiling the cellular activities of molecular libraries

Jonathan S. Melnick, Jeff Janes, Sung Joon Kim, Jim Chang, Daniel G. Sipes, Drew Gunderson, Laura Jarnes, Jason Matzen, Michael Garcia, Tami Hood, Ronak Beigi, Gang Xia, Richard A. Harig, Hayk Asatryan, S. Frank Yan, Yingyao Zhou, Xiang-ju Gu, Alham Saadat, Vicki Zhou, Frederick J. King, Christopher M. Shaw, Andrew I. Su, Robert T. Downs, Nathanael S. Gray, Peter G. Schultz, Markus Warmuth, Jeremy S. Caldwell

Citations: 185 • 2006

A FRET-Based Assay Platform for Ultra-High Density Drug Screening of Protein Kinases and Phosphatases

Steven Rodems, Brian D. Hamman, Christina M. Lin, Jane Zhao, Sundeep Shah, David K. Heidary, Lew Makings, Jeffrey H. Stack, Brian A. Pollok

Citations: 160 • 2002

Delineation of Type I Protein Kinase A-selective Signaling Events Using an RI Anchoring Disruptor

Cathrine R. Carlson, Birgitte Lygren, Torunn Berge, Naoto Hoshi, Wei Wong, Kjetil Taskén, John D. Scott

Citations: 154 • 2006

Tumor Necrosis Factor-related Weak Inducer of Apoptosis Augments Matrix Metalloproteinase 9 (MMP-9) Production in Skeletal Muscle through the Activation of Nuclear Factor-κB-inducing Kinase and p38 Mitogen-activated Protein Kinase

Hong Li, Ashwani Mittal, Pradyut K. Paul, Mukesh Kumar, Daya Shankar Srivastava, Suresh C. Tyagi, Ashok Kumar

Citations: 113 • 2008

A Homogeneous Fluorescence Polarization Assay Adaptable for a Range of Protein Serine/Threonine and Tyrosine Kinases

Elizabeth A. Gaudet, Kuo‐Sen Huang, Yan Zhang, Wei Huang, David Mark, J. Richard Sportsman

Citations: 74 • 2003

Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity

Jiefei Tong, Sabine Elowe, Piers Nash, Tony Pawson

Citations: 70 • 2003

Image-based Screening Identifies Novel Roles for IκB Kinase and Glycogen Synthase Kinase 3 in Axonal Degeneration

Josiah Gerdts, Yo Sasaki, Bhupinder P. S. Vohra, Jayne Marasa, Jeffrey Milbrandt

Citations: 69 • 2011

Dual Specificity A-kinase Anchoring Proteins (AKAPs) Contain an Additional Binding Region That Enhances Targeting of Protein Kinase A Type I

Elisabeth Jarnæss, Anja Ruppelt, Anne Jorunn Stokka, Birgitte Lygren, John D. Scott, Kjetil Taskén

Citations: 66 • 2008

Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities

Marta Sanz-Garciéa, Inmaculada Loépez-Saénchez, Pedro A. Lazo

Citations: 65 • 2008

A Solid-Phase Assay for the Determination of Protein Tyrosine Kinase Activity of c-src Using Scintillating Microtitration Plates

Albert Braunwalder, Donna Yarwood, Tony Hall, Martin Missbach, Kenneth E. Lipson, Matthew A. Sills

Citations: 59 • 1996

Regulation of Casein Kinase-2 (CK2) Activity by Inositol Phosphates

Lev Solyakov, Kelvin Cain, B. M. Tracey, Rebekah Jukes, Andrew M. Riley, Barry V. L. Potter, Andrew B. Tobin

Citations: 52 • 2004

Merlin Links to the cAMP Neuronal Signaling Pathway by Anchoring the RIβ Subunit of Protein Kinase A

Mikaela Grönholm, Lutz Vossebein, Cathrine R. Carlson, Juha Kuja‐Panula, Tambet Teesalu, Kaija Alfthan, Antti Vaheri, Heikki Rauvala, Friedrich W. Herberg, Kjetil Taskén, Olli Carpén

Citations: 52 • 2003

Adenylate Kinase 1 Deficiency Induces Molecular and Structural Adaptations to Support Muscle Energy Metabolism

Edwin Janssen, Ad de Groof, Mietske Wijers, Jack Fransen, Petras P. Dzeja, André Terzic, Bé Wieringa

Citations: 51 • 2003

A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay

Kevin R. Kupcho, Richard L. Somberg, Bob Bulleit, Said A. Goueli

Citations: 49 • 2003

High-Throughput Screening with Immobilized Metal Ion Affinity-Based Fluorescence Polarization Detection, A Homogeneous Assay for Protein Kinases

Elma E.M.G. Loomans, Antoon M. van Doornmalen, Jesse W.Y. Wat, Guido J.R. Zaman

Citations: 43 • 2003

A set of ligation-independent in vitro translation vectors for eukaryotic protein production

Viola Bardóczy, Viktória Géczi, Tatsuya Sawasaki, Yaeta Endo, Tamás Mészáros

Citations: 33 • 2008

Kinase-dependent Regulation of Inositol 1,4,5-Trisphosphate-dependent Ca2+ Release during Oocyte Maturation

Lu Sun, Shirley Haun, Richard C. Jones, Ricky D. Edmondson, Khaled Machaca

Citations: 31 • 2009

A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha

Nivedita Sengupta, Marko Jović, Elena Barnaeva, David W. Kim, Xin Hu, Noel Southall, Milan Dejmek, Ivana Mejdrová, Radim Nencka, Adriana Bäumlová, Dominika Chalupská, Evžen Bouřa, Marc Ferrer, Juan Marugán, Tamás Balla

Citations: 28 • 2019

Microsomal Prostaglandin E2 Synthase-1 Is Induced by Conditional Expression of RET/PTC in Thyroid PCCL3 Cells through the Activation of the MEK-ERK Pathway

Efisio Puxeddu, Norisato Mitsutake, Jeffrey A. Knauf, Sonia Moretti, Hei W. Kim, Karen A. Seta, Diane E. Brockman, Leslie Myatt, David E. Millhorn, James A. Fagin

Citations: 26 • 2003