Mauricio Valerio-Santiago

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About

Mauricio Valerio-Santiago is a pioneering researcher in the fields of tissue engineering, biofabrication, and age-related disease modeling. His major contributions center on the development of advanced 3D-bioengineered models of human skeletal muscle, specifically designed to recapitulate the phenotypic features of aging. This work provides a critical platform for drug testing, enabling more accurate preclinical evaluation of therapeutics for sarcopenia and other muscle-wasting conditions. His most cited paper, "3D-bioengineered model of human skeletal muscle tissue with phenotypic features of aging for drug testing purposes" (2021, 28 citations), demonstrates his impact in creating physiologically relevant in vitro systems. Additionally, his development of a 3D-printed drug testing platform (2020, 4 citations) further showcases his innovative approach to integrating additive manufacturing with tissue engineering. Valerio-Santiago’s research is instrumental in bridging the gap between traditional cell culture and in vivo models, offering flexible, versatile tools for evaluating tissue differentiation, functionality, and force measurement. His work holds significant promise for advancing bio-hybrid robotics and personalized medicine for aging populations.