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About

Manabu Tamura is a pioneering neurosurgeon and researcher whose work sits at the intersection of precision robotics and advanced intraoperative technology for brain tumor treatment. His major contributions center on the clinical implementation and conceptual advancement of robotic Gamma Knife radiosurgery, particularly with the world’s first fully robotized Leksell Gamma Knife Perfexion. Tamura developed the original concept of “robotic gamma knife microradiosurgery,” leveraging the Automatic Positioning System to achieve unprecedented accuracy in treating complex cranial lesions. His landmark 2009 paper on the Perfexion system (92 citations) established a new standard for frameless, high-precision radiosurgery. In a 2012 study of 120 cases, he demonstrated outstanding outcomes for benign cavernous sinus tumors using this technique. Beyond radiosurgery, Tamura has been instrumental in advancing information-guided surgery for intracranial gliomas, contributing to the Intelligent Operating Theater at Tokyo Women’s Medical University, which has treated over 1,000 patients. His work bridges the gap between robotic precision and real-time surgical guidance, making him a key figure in modern, minimally invasive neurosurgery.