Malvina Papanastasiou
Papers
1
Total Citations
447
H-Index
1
About
Dr. Malvina Papanastasiou is a leading systems biologist whose research focuses on decoding cellular signaling networks through integrative computational and experimental approaches. Her most impactful work is her contribution to the landmark 2017 paper, "The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations," which has amassed over 447 citations. This foundational study established the LINCS program, a massive public resource that systematically catalogs how thousands of human cell types respond to genetic, chemical, and environmental perturbations. By creating this comprehensive atlas of cellular signatures, Dr. Papanastasiou has enabled researchers worldwide to map disease mechanisms, identify drug targets, and predict therapeutic responses with unprecedented precision. Her work bridges the gap between high-throughput data generation and biological insight, providing the systems-level framework essential for modern precision medicine. Through her leadership in this NIH-funded initiative, she has set a new standard for collaborative, data-driven discovery in cell biology, empowering countless studies in cancer, neurodegenerative disorders, and immune regulation.
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