Keith S. Wilson
Papers
4
Total Citations
92
H-Index
4
About
Keith S. Wilson is a structural biologist whose research sits at the intersection of X-ray crystallography, structural genomics, and high-throughput proteomics. His most notable contributions stem from his involvement in Structural Proteomics in Europe (SPINE), an ambitious collaborative initiative aimed at systematically determining the three-dimensional structures of proteins from biomedically significant organisms. Wilson has played a central role in structural studies of *Bacillus anthracis*, the bacterium responsible for anthrax, helping to elucidate the crystal structures of key proteins such as dihydrodipicolinate synthase (47 citations) and PurE (12 citations) — enzymes essential to bacterial survival and therefore attractive targets for therapeutic intervention. His collaborative work applying high-throughput technologies to *B. anthracis* proteomics (27 citations) further demonstrated the power of industrialized structural biology pipelines in tackling pathogens of global concern. Wilson has also contributed to the informatics infrastructure underpinning modern structural biology, co-developing xtalPiMS, a web-based platform for managing and monitoring crystallization trials at scale. Together, his body of work reflects a career dedicated to accelerating the discovery of protein structures with direct relevance to human health and biosecurity.
Research Focus
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Top Papers
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