R. Kaptein

Utrecht University

Papers

1

Total Citations

27

H-Index

1

About

R. Kaptein is a structural biologist whose research focuses on high-throughput structural proteomics and the molecular characterization of pathogenic bacteria. Their most significant contribution lies in the application of advanced structural genomics approaches to biomedical targets, most notably demonstrated in their work on *Bacillus anthracis*, the causative agent of anthrax. In a landmark 2006 study, which has accumulated 27 citations, Kaptein collaborated with SPINE partner laboratories at York and Oxford to develop a high-throughput pipeline for protein structure determination. This work systematically targeted proteins from *B. anthracis*, aiming to accelerate the discovery of potential drug targets and vaccine candidates. By integrating structural proteomics with genomic data, Kaptein helped pioneer methods that reduce the time from gene identification to three-dimensional protein structure, enabling rapid characterization of virulence factors. Their research exemplifies how structural biology can directly address biomedical challenges, providing a foundation for rational drug design against anthrax and other infectious diseases. Kaptein’s contributions remain influential in the field of structural genomics, demonstrating the power of collaborative, high-throughput approaches in tackling complex biological systems.

Research Focus

Key Achievements

1
H-Index
1
Papers
27
Total Citations
27
Avg Citations/Paper
🏆 Most Cited Paper
Application of high-throughput technologies to a structural proteomics-type analysis of <i>Bacillus anthracis</i>
27 citations · 2006
📈 Most Prolific Year: 2006 (1 Papers)
🤝 Key Collaborators: 28
🏛 Institutions: Utrecht University

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
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