Papers
4
Total Citations
227
H-Index
3
About
James Inglese is a pioneering researcher whose career sits at the intersection of pharmacology, chemical biology, and drug discovery technology. Best known for his foundational work in high-throughput screening (HTS), Inglese has been instrumental in adapting and advancing robotic and automated platforms that enable researchers to rapidly evaluate thousands of compounds for biological activity. His 2008 paper on robotic platforms for quantitative HTS, which has garnered 157 citations, stands as a landmark contribution that helped democratize screening technologies within academic institutions — a setting where the pressures and priorities of drug development differ markedly from industry. His earlier work on miniaturizing the Hepatitis C virus RNA polymerase assay and identifying metabotropic glutamate receptor antagonists through automated systems demonstrated his ability to translate complex biological problems into scalable, practical screening solutions. More recently, Inglese has turned his attention to the broader challenges of translational research, exploring the conceptual and practical hurdles involved in target-based drug discovery for neuropathic pain. Across his career, his contributions have equipped the biomedical research community with essential tools to bridge the gap between basic science and therapeutic development.
Research Focus
Key Achievements
Top Papers
- 1A Robotic Platform for Quantitative High-Throughput Screening157 citations · 2008
- 2
- 3
- 4