Graeme E. Walker
Papers
1
Total Citations
22
H-Index
1
About
Graeme E. Walker is a leader in assay development and laboratory automation, whose work has been instrumental in transforming drug discovery at AstraZeneca. His primary research focuses on the implementation and optimization of acoustic droplet ejection (ADE) technology for high-throughput screening. Walker’s major contribution lies in pioneering the adoption of Labcyte Echo ADE systems, which have become the global standard for compound dosing across AstraZeneca’s research and development. His 2015 paper, "Implementation and Challenges of Direct Acoustic Dosing into Cell-Based Assays," with 22 citations, details the critical transition from traditional liquid handling to this non-contact, precise method, overcoming key challenges in cell-based assays. This work has significantly improved assay reproducibility and miniaturization, accelerating the drug discovery pipeline. Walker’s achievements include leading the integration of this technology since 2005, establishing a paradigm shift that now underpins biochemical and cell-based screening worldwide, making him a pivotal figure in modern pharmaceutical automation.
Research Focus
Key Achievements
Top Papers
- 1