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Federica Bertolucci is a leading researcher in neurorehabilitation, with a focus on stroke recovery and motor function restoration. Her work centers on understanding neuroplastic changes following brain ischemia and leveraging robotic technologies to enhance rehabilitation outcomes. Bertolucci’s most cited paper (2017, 243 citations) provides a foundational review of how spared brain areas reorganize after stroke, offering critical insights for developing more effective rehabilitation strategies. She has pioneered the use of robotic gait training, demonstrating significant improvements in motor skills and quality of life for patients with hereditary spastic paraplegia (2015, 43 citations) and post-stroke individuals (2015, 37 citations). Her research also explores the mechanisms behind robot-assisted therapy, including modifications in motor unit firing, and extends to upper limb rehabilitation with robotic exoskeletons. Notably, Bertolucci has investigated EEG biomarkers to predict motor improvement after robotic rehabilitation (2018), advancing personalized neurorehabilitation. With a strong translational impact, her work bridges neuroscience and engineering, offering hope for millions affected by neurological disorders.