Eric Gottwald
Papers
1
Total Citations
26
H-Index
1
About
Eric Gottwald is a leading figure in bioprocess engineering, with a core focus on advancing the purification and manufacturing of cell-based therapeutic products. His major contributions center on the development of high-throughput, scalable downstream processing strategies, particularly through the innovative application of aqueous two-phase systems (ATPS). His most-cited work, "High-throughput downstream process development for cell-based products using aqueous two-phase systems" (2016, 26 citations), provides a foundational methodology for rapidly optimizing the separation of living cells from complex bioreactor harvests—a critical bottleneck in cell therapy production. By demonstrating how ATPS can replace costly, low-yield centrifugation steps, Gottwald’s research directly addresses the industrial need for cost-effective, continuous manufacturing. His work is notable for bridging fundamental phase-separation science with practical process development, enabling researchers to screen hundreds of conditions in parallel. This approach has profound implications for the scalability of personalized medicines, such as CAR-T cell therapies. With his contributions, Gottwald has established himself as a key innovator in the transition of cell-based products from lab-scale to clinical and commercial reality.
Research Focus
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Top Papers
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