Sarah C. Zimmermann
Papers
3
Total Citations
42
H-Index
3
About
Sarah C. Zimmermann is a bioprocess engineer whose research sits at the intersection of cell therapy manufacturing and downstream processing innovation. Her work has focused primarily on developing scalable, cost-effective purification strategies for cell-based products using aqueous two-phase systems (ATPS), a field of growing urgency as regenerative medicine and cell therapies advance toward clinical application. Zimmermann's most significant contributions address a critical bottleneck in the translation of cell-based therapies from laboratory research to clinical reality: the lack of robust, preparative-scale downstream processing methods. Her high-throughput approach to ATPS development, published in 2016 and accumulating over 26 citations, demonstrated that gentle, label-free, and scalable cell purification is achievable without the complexity and cost of conventional separation techniques. A companion case study further validated this methodology in applied settings. Her 2017 investigation into the influence of polymer molecular weight and tie-line length on cell separation resolution added important mechanistic depth to the field, helping researchers fine-tune ATPS conditions for diverse cell populations. Collectively, her body of work has provided the cell therapy community with practical, translatable tools that bridge fundamental science and clinical manufacturing, earning her recognition as a thoughtful contributor to an emerging and high-impact discipline.
Research Focus
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Top Papers
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