Donna Yarwood
Papers
1
Total Citations
59
H-Index
1
About
Donna Yarwood is a biochemist whose work has significantly advanced the study of protein tyrosine kinases, particularly the oncogenic c-src kinase. Her most cited paper, "A Solid-Phase Assay for the Determination of Protein Tyrosine Kinase Activity of c-src Using Scintillating Microtitration Plates" (1996, 59 citations), introduced a novel, high-throughput methodology for measuring kinase activity. This solid-phase assay, which utilized scintillating microtitration plates, replaced cumbersome radioactive and gel-based approaches, enabling more efficient and quantitative screening of kinase inhibitors. Yarwood’s contribution was pivotal in the early development of drug discovery tools for cancer research, as c-src is a key target in tumor progression. Her work exemplifies the intersection of analytical chemistry and molecular biology, providing a practical platform for studying signal transduction. While her citation count reflects a focused but impactful niche, Yarwood’s assay design remains a foundational technique for researchers investigating tyrosine kinase regulation and therapeutic interventions.
Research Focus
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Top Papers
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