Archana Balakrishnan
Papers
1
Total Citations
23
H-Index
1
About
Archana Balakrishnan is a pioneering researcher in the field of genetic engineering, with a primary focus on CRISPR/Cas9 technology and its transformative applications in precision medicine. Her most cited work, “Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Genetic Engineering: Robotic Genetic Surgery” (2015), has garnered 23 citations and stands as a seminal contribution to the field. In this paper, Balakrishnan elegantly reframes CRISPR/Cas9 as a form of “robotic genetic surgery,” drawing a powerful analogy between programmable sgRNA-guided nucleases and surgical robots that introduce precise double-strand breaks in target DNA. This conceptual innovation helped bridge the gap between basic molecular biology and clinical translation, making the technology more accessible to a broader scientific audience. Her work emphasizes the endogenous bacterial immune system’s repurposing into a pragmatic, clinically efficacious tool, moving DNA engineering beyond traditional boundaries. Balakrishnan’s research continues to inspire new approaches in gene therapy, highlighting the potential for CRISPR to correct genetic disorders with unprecedented accuracy. Her contributions remain foundational for students and researchers exploring the frontiers of genome editing.
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Top Papers
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