In silico

Plant natural products: Back to the future or into extinction?

James D. McChesney, Sylesh K. Venkataraman, John T. Henri

Citations: 376 • 2007

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

Terence I. Moy, Annie L. Conery, Jonah Larkins‐Ford, Gang Wu, Ralph Mazitschek, Gabriele Casadei, Kim Lewis, Anne E. Carpenter, Frederick M. Ausubel

Citations: 210 • 2009

High resolution melting analysis for gene scanning

Maria Erali, Carl T. Wittwer

Citations: 167 • 2010

Exploration of Enzyme Diversity by Integrating Bioinformatics with Expression Analysis and Biochemical Characterization

Pavel Vaňáček, Eva Šebestová, Petra Bábková, Šárka Bidmanová, Lukáš Daniel, Pavel Dvořák, Veronika Štěpánková, Radka Chaloupková, Jan Brezovský, Zbyněk Prokop, Jiřı́ Damborský

Citations: 93 • 2018

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping

Simon Unthan, Andreas Radek, Wolfgang Wiechert, Marco Oldiges, Stephan Noack

Citations: 86 • 2015

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

Laurent Hoffer, Yu. V. Voitovich, Brigitt Raux, Kendall Carrasco, Christophe Müller, Alexey Yu. Fedorov, Carine Derviaux, Agnès Amouric, S. Betzi, Dragos Horvath, Alexandre Varnek, Yves Collette, Sébastien Combes, Philippe Roche, Xavier Morelli

Citations: 72 • 2018

A structure‐based strategy for discovery of small ligands binding to functionally unknown proteins: Combination of <b><i>in silico</i></b> screening and surface plasmon resonance measurements

Naoei Yoshitani, Kazuhito Satou, Kazuki Saito, Sakura Suzuki, Hideki Hatanaka, Motoaki Seki, Kazuo Shinozaki, Hiroshi Hirota, Shigeyuki Yokoyama

Citations: 64 • 2005

Protein engineering via Bayesian optimization-guided evolutionary algorithm and robotic experiments

Ruyun Hu, Lihao Fu, Yongcan Chen, Junyu Chen, Yu Qiao, Tong Si

Citations: 60 • 2022

The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones

Paul Workman

Citations: 58 • 2003

THUMB-LOOPS UP FOR CATALYSIS: A STRUCTURE/FUNCTION INVESTIGATION OF A FUNCTIONAL LOOP MOVEMENT IN A GH11 XYLANASE

Gabriel Paës, Juan Cortés, Thierry Siméon, Michael O’Donohue, V.H. Tran

Citations: 29 • 2012

A Comparison between Mouse,<i>In Silico</i>, and Robot Odor Plume Navigation Reveals Advantages of Mouse Odor Tracking

Ankita Gumaste, Guillermo Coronas‐Samano, James Hengenius, R. Axman, Erin Connor, Keeley L. Baker, Bard Ermentrout, John P. Crimaldi, Justus V. Verhagen

Citations: 27 • 2020

Exploring Host-Microbiome Interactions using an in Silico Model of Biomimetic Robots and Engineered Living Cells

Keith C. Heyde, Warren C. Ruder

Citations: 25 • 2015

New approaches in identifying drugs to inactivate oncogene products

Ruiwu Liu, Ching‐Yi Hsieh, Kit S. Lam

Citations: 21 • 2004

Open PHACTS computational protocols for <i>in silico</i> target validation of cellular phenotypic screens: knowing the knowns

Daniela Digles, Barbara Zdrazil, Jean‐Marc Neefs, Herman van Vlijmen, Christian Herhaus, Andrei Caracoti, José Brea, B. Roibás, Marı́a Isabel Loza, Núria Queralt-Rosiñach, Laura I. Furlong, Anna Gaulton, Luca Bartek, Stefan Senger, Christine Chichester, Ola Engkvist, Chris T. Evelo, Natalie Franklin, D. Marren, Gerhard F. Ecker, Edgar Jacoby

Citations: 18 • 2016

In silico actuation performance investigation of dielectric elastomers with TPMS geometries

Mostafa Baghani, Majid Baniassadi, Mahdi Bodaghi

Citations: 14 • 2024

Multifragment DNA Assembly of Biochemical Pathways via Automated Ligase Cycling Reaction

Christopher Robinson, Mark S. Dunstan, Neil Swainston, James Titchmarsh, Eriko Takano, Nigel S. Scrutton, Adrian J. Jervis

Citations: 14 • 2018

Quantitative high-throughput phenotypic screening for environmental estrogens using the E-Morph Screening Assay in combination with in silico predictions

Saskia Klutzny, Marja Kornhuber, Andrea Morger, Gilbert Schönfelder, Andrea Volkamer, Michael Oelgeschläger, Sebastian Dunst

Citations: 12 • 2021

In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot

Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris‐Drouin, P. Brian Hardy, Kenneth H. Pearce, Dmitri Kireev

Citations: 11 • 2024

Digital circuits and neural networks based on acid-base chemistry implemented by robotic fluid handling

Ahmed Agiza, Kady Oakley, Jacob K. Rosenstein, Brenda M. Rubenstein, Eunsuk Kim, Marc D. Riedel, Sherief Reda

Citations: 11 • 2023

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Stan Pasyk, Steven V. Molinski, Wilson Yu, Paul D. W. Eckford, Christine E. Bear

Citations: 11 • 2012