Bioprocess

Miniature bioreactors: current practices and future opportunities.

Jonathan Ian Betts, Frank Baganz

Citations: 281 • 2006

Microbioreactor Systems for Accelerated Bioprocess Development

Johannes Hemmerich, Stephan Noack, Wolfgang Wiechert, Marco Oldiges

Citations: 176 • 2017

An automated workflow for enhancing microbial bioprocess optimization on a novel microbioreactor platform

Peter Rohe, Deepak Venkanna, Britta Kleine, Roland Freudl, Marco Oldiges

Citations: 138 • 2012

Microbioreactor arrays with integrated mixers and fluid injectors for high-throughput experimentation with pH and dissolved oxygen control

Harry L. T. Lee, Paolo Boccazzi, Rajeev J. Ram, Anthony J. Sinskey

Citations: 134 • 2006

How does the Internet of Things (IoT) help in microalgae biorefinery?

Kexin Wang, Kuan Shiong Khoo, Hui Yi Leong, Dillirani Nagarajan, Kit Wayne Chew, Huong Yong Ting, Anurita Selvarajoo, Jo‐Shu Chang, Pau Loke Show

Citations: 128 • 2021

Novel micro‐bioreactor high throughput technology for cell culture process development: Reproducibility and scalability assessment of fed‐batch CHO cultures

Ashraf Amanullah, José M. Otero, Mark Mikola, Amy Hsu, Jinyou Zhang, John Auniņš, H. Brett Schreyer, James A. Hope, Adele Russo

Citations: 110 • 2010

Online optimal experimental re‐design in robotic parallel fed‐batch cultivation facilities

Mariano Nicolás Cruz Bournazou, Tilman Barz, David Nickel, Diana C. López Cárdenas, Florian Glauche, Andreas Knepper, Peter Neubauer

Citations: 104 • 2016

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping

Simon Unthan, Andreas Radek, Wolfgang Wiechert, Marco Oldiges, Stephan Noack

Citations: 86 • 2015

Recent advances in fed-batch microscale bioreactor design

Sarah Teworte, Koray Malcı, Laura E. Walls, Murni Halim, Leonardo Rios‐Solis

Citations: 67 • 2021

Automation of cell line development

Kristina Lindgren, Andrea Salmén, Mats Lundgren, Lovisa Bylund, Åsa Ebler, Eric Fäldt, Lina Sörvik, Christel Fenge, Ulrica Skoging-Nyberg

Citations: 47 • 2009

An automated robotic platform for rapid profiling oligosaccharide analysis of monoclonal antibodies directly from cell culture

Margaret Doherty, Jonathan Bones, Niaobh McLoughlin, Jayne E. Telford, Bryan J. Harmon, Michael R. DeFelippis, Pauline M. Rudd

Citations: 46 • 2013

Robotic Platform for Parallelized Cultivation and Monitoring of Microbial Growth Parameters in Microwell Plates

Andreas Knepper, Michael Heiser, Florian Glauche, Peter Neubauer

Citations: 41 • 2014

Implementation of a Fully Automated Microbial Cultivation Platform for Strain and Process Screening

Nils H. Janzen, Gerald Striedner, Johanna Jarmer, Martin Voigtmann, Sandra Abad, Daniela Reinisch

Citations: 40 • 2019

Automation of a Nile red staining assay enables high throughput quantification of microalgal lipid production

Holger Morschett, Wolfgang Wiechert, Marco Oldiges

Citations: 37 • 2016

On-line multiple component analysis for efficient quantitative bioprocess development

Christian Dietzsch, Oliver Spadiut, Christoph Herwig

Citations: 34 • 2012

Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort

Alex J. Spice, Rochelle Aw, Daniel G. Bracewell, Karen M. Polizzi

Citations: 33 • 2020

Delay and dispersion in an in situ membrane probe for bioreactors

Lars H. Christensen, Jens Nielsen, John Villadsen

Citations: 31 • 1991

Screening of a genome‐reduced <i>Corynebacterium glutamicum</i> strain library for improved heterologous cutinase secretion

Johannes Hemmerich, Mohamed E. Labib, Carmen Steffens, Sebastian J. Reich, Marc Weiske, Meike Baumgart, Christian Rückert, Matthias Ruwe, Daniel Siebert, Volker F. Wendisch, Jörn Kalinowski, Wolfgang Wiechert, Marco Oldiges

Citations: 29 • 2020

Accelerated Bioprocess Development of Endopolygalacturonase-Production with Saccharomyces cerevisiae Using Multivariate Prediction in a 48 Mini-Bioreactor Automated Platform

Annina Sawatzki, Sebastian Hans, Harini Narayanan, Benjamin Haby, Niels Krausch, Michael Sokolov, Florian Glauche, Sebastian L. Riedel, Peter Neubauer, Mariano Nicolás Cruz Bournazou

Citations: 28 • 2018

In-line product quality monitoring during biopharmaceutical manufacturing using computational Raman spectroscopy

Jiarui Wang, Jingyi Chen, Joey Studts, Gang Wang

Citations: 27 • 2023