Marc L. Pusey

Papers

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About

Marc L. Pusey is a distinguished researcher whose work sits at the compelling intersection of protein crystallization, automated imaging systems, and data analytics. His research has been instrumental in advancing high-throughput approaches to understanding the complex conditions required for successful protein crystal formation — a critical step in structural biology and drug discovery. Pusey's most influential contribution, "Data Analytics for Protein Crystallization" (2017, 15 citations), demonstrates his commitment to harnessing computational methods to extract meaningful insights from the vast datasets generated by modern crystallization experiments. This work complements his earlier publication, "CrystPro: Spatiotemporal Analysis of Protein Crystallization Images" (2015, 12 citations), which addressed the challenge of systematically analyzing thousands of experimental images produced by robotic, high-throughput crystallization platforms. Together, these papers reflect a cohesive research vision: automating and intelligently interpreting protein crystallization workflows to accelerate scientific discovery. His work on robotic image acquisition further underscores his dedication to streamlining laboratory processes through technology. For students and researchers navigating structural biology, Pusey's contributions offer a valuable roadmap for applying data-driven methodologies to one of biochemistry's most technically demanding challenges.