Papers
19
Total Citations
7,259
H-Index
13
About
Leigh R. Hochberg is a pioneering neurologist and neuroscientist whose work sits at the intersection of neuroengineering and clinical medicine, focusing on restoring function to people with paralysis. As the lead investigator of the BrainGate clinical trials, his major contributions have demonstrated that people with tetraplegia can directly control external devices using neural activity recorded from the motor cortex. His landmark 2006 paper, "Neuronal ensemble control of prosthetic devices by a human with tetraplegia" (3,324 citations), provided the first evidence that intracortical signals could be used to control a prosthetic device in a human. This was followed by the equally influential 2012 study "Reach and grasp by people with tetraplegia using a neurally controlled robotic arm" (2,730 citations), which showed participants could perform functional tasks like drinking from a bottle. Hochberg's work has also addressed critical engineering challenges, including signal processing to reduce artifacts from functional electrical stimulation and the development of recurrent neural networks for bimanual control. His research has fundamentally advanced the field of brain-computer interfaces, moving it from theoretical possibility to clinical reality, and has given new hope to individuals living with paralysis.
Research Focus
Key Achievements
Top Papers
- 1Neuronal ensemble control of prosthetic devices by a human with tetraplegia3,324 citations · 2006
- 2Reach and grasp by people with tetraplegia using a neurally controlled robotic arm2,730 citations · 2012
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- 9Brain control of bimanual movement enabled by recurrent neural networks44 citations · 2024
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