G. Steven Bova
Papers
1
Total Citations
20
H-Index
1
About
G. Steven Bova is a leading figure in prostate cancer research, whose work bridges the critical gap between molecular biology and clinical pathology. His primary research areas include prostate cancer genomics, the development of novel tissue preservation methods for molecular diagnostics, and the integration of histomorphologic data with molecular phenotypes. Bova’s major contribution lies in pioneering the validation of PAXgene fixation as a viable alternative to traditional formalin fixation. His landmark 2017 study, cited over 20 times, demonstrated that PAXgene-fixed paraffin-embedded (PFPE) tissue preserves high-quality DNA, RNA, and proteins, enabling robust molecular analysis without compromising diagnostic surgical pathology. This breakthrough addresses a long-standing challenge in the field: the degradation of biomolecules in standard FFPE samples. By showing that PFPE can support both routine histology and advanced genomic studies, Bova’s work has paved the way for more accurate biomarker discovery and personalized treatment strategies in prostate cancer. His research is essential for any student or researcher aiming to understand how tissue handling directly impacts the fidelity of molecular data in cancer studies.
Research Focus
Key Achievements
Top Papers
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