Andrew Leithead

Merck & Co., Inc., Rahway, NJ, USA (United States)

Papers

1

Total Citations

36

H-Index

1

About

Andrew Leithead’s research focuses on pharmaceutical formulation and biopharmaceutics, with a particular emphasis on understanding how the composition of intestinal media influences the solubility of poorly soluble drug compounds. His most-cited work, a 2017 study employing a design of experiments approach, systematically investigated the effects of simulated intestinal fluid components on drug solubility. This contribution is critical for improving the predictive accuracy of in vitro dissolution tests, thereby aiding the development of more effective oral drug formulations. With 36 citations, this paper has provided a foundational framework for researchers seeking to refine biorelevant media for solubility screening. Leithead’s work bridges the gap between laboratory simulations and physiological conditions, offering practical insights for both academic and industrial pharmaceutical scientists. His careful, data-driven methodology underscores his commitment to enhancing the reliability of early-stage drug development, making his research a valuable resource for students and professionals aiming to optimize formulation strategies.

Research Focus

Key Achievements

1
H-Index
1
Papers
36
Total Citations
36
Avg Citations/Paper
🏆 Most Cited Paper
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
36 citations · 2017
📈 Most Prolific Year: 2017 (1 Papers)
🤝 Key Collaborators: 6
🏛 Institutions: Merck & Co., Inc., Rahway, NJ, USA (United States)

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
Content generated · 12 days ago