Andrea Ruiz-Valdepenas Martin de Almagro
Papers
1
Total Citations
109
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1
About
Andrea Ruiz-Valdepenas Martin de Almagro is a leading researcher in the field of liquid biopsy and circulating tumor DNA (ctDNA) analysis, with a focus on improving the pre-analytical and technical workflows essential for noninvasive cancer management. Her most-cited work, a 2018 study with 109 citations, systematically investigates how collection and processing procedures impact plasma cell-free DNA (cfDNA) levels, highlighting the critical challenge of leukocyte lysis that can obscure the minor ctDNA fraction. This contribution has provided foundational guidance for standardizing pre-analytical protocols, directly enhancing the reliability of liquid biopsy assays. Beyond this, her research advances the detection of rare tumor-derived genetic material, enabling more accurate monitoring of cancer progression and treatment response. With her work cited by peers developing clinical applications, Ruiz-Valdepenas Martin de Almagro has established herself as a key figure in translating liquid biopsy from bench to bedside, driving improvements in sensitivity and reproducibility that benefit both researchers and patients.
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