PD61-05 RANDOMIZED TRIAL COMPARING URINARY CONTINENCE RATES BETWEEN PELVIC MUSCLES EXERCISES WITH AND WITHOUT TRANS-PELVIC MAGNETIC STIMULATION AFTER ROBOTIC ASSISTED RADICAL PROSTATECTOMY

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You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy V (PD61)1 Sep 2021PD61-05 RANDOMIZED TRIAL COMPARING URINARY CONTINENCE RATES BETWEEN PELVIC MUSCLES EXERCISES WITH AND WITHOUT TRANS-PELVIC MAGNETIC STIMULATION AFTER ROBOTIC ASSISTED RADICAL PROSTATECTOMY Mattia Nicola Sangalli, Paolo Vota, Matteo Zanoni, Giovanni Toia, Cinzia Mazzieri, Alberto Mandressi, Fabio Grizzi, Pier Paolo Avolio, Nicolò Buffi, Giovanni Lughezzani, Pieve Emanuele, Massimo Lazzeri, Giorgio Guazzoni, Pieve Emanuele, and Gian Luigi Taverna Mattia Nicola SangalliMattia Nicola Sangalli , Paolo VotaPaolo Vota , Matteo ZanoniMatteo Zanoni , Giovanni ToiaGiovanni Toia , Cinzia MazzieriCinzia Mazzieri , Alberto MandressiAlberto Mandressi , Fabio GrizziFabio Grizzi , Pier Paolo AvolioPier Paolo Avolio , Nicolò BuffiNicolò Buffi , Giovanni LughezzaniGiovanni Lughezzani , Pieve EmanuelePieve Emanuele , Massimo LazzeriMassimo Lazzeri , Giorgio GuazzoniGiorgio Guazzoni , Pieve EmanuelePieve Emanuele , and Gian Luigi TavernaGian Luigi Taverna View All Author Informationhttps://doi.org/10.1097/JU.0000000000002098.05AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Prostate cancer is the second most commonly diagnosed cancer in men. RARP represents the primary choice of treatment for prostate cancer and urinary incontinence (UI) remains the main postoperative side effect, whose prevalence ranges from 4% to 31%. Different therapeutic approaches for the treatment of UI have been used like pelvic muscles exercises (PMEs), electrical stimulation (ES) and biofeedback (BFB), even if none of them has been reported better than others, because of the lack of randomized trial. rTPM is a passive training program based on electromagnetic stimulation of pelvic floor muscle groups and give a better response ratio from usually inactive muscle fibers and quickens reflex response. We present a randomized controlled trial enrolling 100 patients undergone RARP between march 2018 and march 2019. The patients were randomly assigned to the treatment group (rTPM+PMEs) or the Control Group (only PMEs).The primary outcome of our study was to evaluate the UC rates between two groups. The secondary outcome is to evaluate the differences in UC recovery between the two groups. METHODS: Patients in rTPM group were trained for PME after removal of the catheter and 1 month after RARP each patient was scheduled for 2 rTPM sessions per week for 8 consecutive weeks for a total of 16 sessions. Patients in Control group were trained for PME after removal of the catheter.All patients were required to fill the Short Form ICIQ- SF questionnaire and the 24-hours pad weight test at 1, 2, 3, 6 and 12 months after surgery and were scheduled for outpatient clinic evaluations. For all patients continence scores were thus assessed prior to the treatment, halfway through and at the end of the treatment. The technology used in the training is certified in the EU as a class 2b CE medical device. Cost per patient was 3000 Euro. RESULTS: There was no statistically significant difference between the two groups (rTPM Group vs Control Group) with respect to patient’s age, BMI, preoperative PSA levels, prostate weight, clinical stage, Gleason score and D’amico risk stratification. In the rTPM group, the UC rates at 1, 2,3,6 and 12 months were 86%, 87%, 90.0%, 96.0% and 98.0 % respectively. In the Control group the UC rates were 88.0%, 88.0% ,92.0%, 97% and 97%, respectively. No statistically significant difference was observed in the two groups at 1, 2, 3,6 and 12 months. 3 (16%) patients in rTPM Group dropped out for severe pelvic pain. CONCLUSIONS: No statistically significant difference was observed in the two groups for UC and UC recovery. The side effects and the cost of the device did not justify routinary use of the rTPM in the clinical practice. Source of Funding: None © 2021 by Americ