Zachary Owyang
Papers
1
Total Citations
94
H-Index
1
About
Zachary Owyang is a pioneering researcher at the intersection of biomedical engineering and drug delivery, best known for his groundbreaking work in developing robotic systems for oral biotherapeutic administration. His key research areas include ingestible robotics, gastrointestinal drug delivery, and the engineering of novel therapeutic platforms that replace painful injections with patient-friendly oral alternatives. Owyang’s most notable contribution is his leadership in the first-in-human clinical trial of a robotic pill for oral delivery of biotherapeutics, published in 2021 and cited 94 times. This study demonstrated the safety, tolerability, and performance of a self-orienting, millimeter-scale device that autonomously deploys a drug-loaded microneedle into the stomach lining, enabling systemic absorption of large-molecule drugs like insulin and monoclonal antibodies. By overcoming the longstanding barrier of gastrointestinal degradation, Owyang’s work has the potential to transform chronic disease management for millions of patients who require daily injections. His research has been recognized for its translational impact, bridging cutting-edge robotics with real-world clinical needs, and continues to inspire new approaches in non-invasive drug delivery.
Research Focus
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Top Papers
- 1