W. B. Sampson
Papers
1
Total Citations
2
H-Index
1
About
W. B. Sampson’s research career is defined by a pivotal contribution to the early days of high-throughput genomics. While at AMGEN, Sampson was instrumental in developing automated systems for reverse transcriptase-polymerase chain reaction (RT-PCR), a critical tool for analyzing gene expression patterns at scale. Their most cited work, "Automated high throughput RT-PCR" (1996), describes a method that allowed researchers to rapidly screen novel genes for therapeutic potential by assessing their in vivo expression. This innovation was a foundational piece of AMGEN’s genome project, enabling the efficient discovery and evaluation of genes with possible clinical value. Though the paper holds a modest 2 citations, its significance lies not in raw numbers but in its role as a practical, early solution to a pressing bottleneck in functional genomics. Sampson’s work represents a key step in moving molecular biology from manual, low-throughput experiments toward the automated, data-rich pipelines that define modern drug discovery and genetic research.
Research Focus
Key Achievements
Top Papers
- 1Automated high throughput RT-PCR2 citations · 1996