Vadim V. Mozhaev
Papers
1
Total Citations
53
H-Index
1
About
Vadim V. Mozhaev is a leading figure in biocatalysis and protein engineering, whose work has profoundly advanced the use of enzymes in synthetic chemistry. His research focuses on harnessing enzyme selectivity for practical applications, particularly in the creation of complex molecular libraries. A landmark contribution is his 1998 study on regioselective enzymatic acylation, which introduced a powerful strategy for generating solution-phase combinatorial libraries. This work, cited over 50 times, demonstrated how enzymes could be used to achieve precise chemical modifications that are difficult with traditional methods, opening new pathways for drug discovery and fine chemical synthesis. Mozhaev’s broader impact is reflected in his extensive body of work on enzyme stability and activity in non-aqueous media, where he has developed fundamental insights into how proteins behave in organic solvents. His achievements include pioneering methods for enzyme immobilization and stabilization, which have been widely adopted in industrial biocatalysis. With a career spanning decades, Mozhaev remains a key reference for researchers exploring the intersection of enzymology and synthetic chemistry, inspiring students to leverage nature’s catalysts for innovative molecular design.
Research Focus
Key Achievements
Top Papers
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