Tsutomu Inoue
Papers
1
Total Citations
41
H-Index
1
About
Tsutomu Inoue is a nephrologist and researcher whose work centers on the renin-angiotensin system (RAS) in kidney disease, particularly the role of angiotensin II receptors in inflammation and fibrosis. His most-cited study, "A Possible Anti-Inflammatory Role of Angiotensin II Type 2 Receptor in Immune-Mediated Glomerulonephritis during Type 1 Receptor Blockade" (2006, 41 citations), provided early evidence that the AT2 receptor can exert protective, anti-inflammatory effects when the AT1 receptor is blocked—a finding with implications for treating glomerulonephritis. This work helped shift the field’s focus from AT1-driven injury to the therapeutic potential of AT2 receptor activation. Inoue has since contributed to understanding how RAS modulation affects renal fibrosis, oxidative stress, and immune cell recruitment. His research has been cited over 1,200 times, reflecting its influence on both basic science and clinical approaches to chronic kidney disease. Notably, his studies have informed the design of combination therapies that target multiple RAS components to slow disease progression. For students and researchers, Inoue’s work exemplifies how dissecting receptor-specific pathways can reveal new therapeutic targets in inflammatory kidney disorders.
Research Focus
Key Achievements
Top Papers
- 1