Therese Seierstad

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About

Therese Seierstad is a leading researcher in prostate cancer imaging, with a focus on improving diagnostic accuracy through advanced MRI and PET techniques. Her work centers on the clinical application of multiparametric imaging to better characterize tumor aggressiveness and local extent. In her landmark 2012 study, she demonstrated the accuracy of routine pelvic MRI using phased-array coils for detecting extraprostatic tumor extension, a critical factor in treatment planning. This work, cited 25 times, established a practical, non-invasive approach to staging that has influenced clinical protocols. More recently, Seierstad has pioneered the integration of dynamic imaging modalities, comparing time-activity curves from 18F-fluciclovine PET with dynamic contrast-enhanced MRI. Her 2018 study, though early in its citation impact, addresses the pressing need to understand whether these techniques provide complementary or redundant information for characterizing primary prostate carcinomas. By systematically evaluating perfusion-phase dynamics of both contrast agents and radiotracers, she is laying the groundwork for more precise, multimodal tumor assessment. Seierstad’s contributions are shaping how clinicians leverage imaging to guide biopsy, risk stratification, and therapeutic decisions in prostate cancer.