Sylvain Moineau
Papers
1
Total Citations
113
H-Index
1
About
Sylvain Moineau is a leading figure in phage biology, with a career-long focus on bacteriophages infecting lactic acid bacteria and the revolutionary CRISPR-Cas systems. His foundational work has profoundly shaped our understanding of phage-host interactions, particularly in the dairy industry, where his research on *Lactococcus lactis* phages has provided critical insights into phage resistance and evolution. His highly cited 2006 paper on the modular structure of phage receptor binding proteins (113 citations) is a landmark contribution, demonstrating how these proteins are assembled from interchangeable modules, a principle that explains host range determination and phage adaptability. Beyond this, Moineau is globally recognized for his pioneering role in characterizing CRISPR-Cas systems as adaptive immune mechanisms in bacteria. His work has been instrumental in elucidating the molecular details of CRISPR-Cas9 function, directly contributing to the development of genome-editing technologies. With a publication record amassing tens of thousands of citations, Moineau’s impact spans fundamental microbiology, industrial applications, and biotechnology, cementing his status as a visionary in the field.
Research Focus
Key Achievements
Top Papers
- 1Modular Structure of the Receptor Binding Proteins of Lactococcus lactis Phages113 citations · 2006