Soichiro Shimoda

Tokyo University of Agriculture and Technology

Papers

Total Citations

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About

Soichiro Shimoda is a developmental biologist whose research centers on single-cell manipulation and gene expression in embryonic stem cells, with a particular focus on understanding early mammalian development at the cellular level. His most cited work, "Semi-quantitative expression and knockdown of a target gene in single-cell mouse embryonic stem cells by high performance microinjection" (2006, 15 citations), introduced a refined microinjection technique that enables precise, semi-quantitative control over gene expression and knockdown in individual mouse embryonic stem cells. This methodological contribution is notable for its high precision and reproducibility, offering researchers a powerful tool to dissect gene function in single cells—a critical capability for studying stem cell pluripotency, differentiation, and early embryogenesis. While his citation count is modest, the work’s impact lies in its technical innovation, providing a foundation for subsequent single-cell studies. Shimoda’s achievements underscore his dedication to advancing experimental approaches in stem cell biology, making his research valuable for scientists exploring cellular heterogeneity and gene regulation in development.