Sneha R. Kabaria
Papers
1
Total Citations
19
H-Index
1
About
Sneha R. Kabaria is a researcher specializing in biopharmaceutical formulation and analytical characterization, with a particular focus on protein stability in lyophilized (freeze-dried) solids. Her most cited work, "Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids" (2019, 19 citations), introduces a novel, semi-automated method that leverages matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) combined with solid-state hydrogen deuterium exchange (ssHDX). This technique enables rapid, high-throughput evaluation of protein physical stability in dried formulations—a critical challenge in developing stable biotherapeutics. By providing a more efficient alternative to traditional, labor-intensive methods, Kabaria’s work advances the ability to screen and optimize lyophilized formulations, directly impacting the shelf-life and efficacy of peptide and protein drugs. Her contributions are particularly valuable for researchers in pharmaceutical sciences and biophysics, offering a practical tool for assessing structural integrity in solid-state systems. With this foundational study, Kabaria has established herself as an emerging voice in the intersection of mass spectrometry and formulation science, paving the way for more robust analytical approaches in biopharmaceutical development.
Research Focus
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Top Papers
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