Shouxi Xu
Papers
1
Total Citations
22
H-Index
1
About
Shouxi Xu is a pioneering pharmacologist whose research centers on prostaglandin receptor signaling and its therapeutic applications in ocular and cellular biology. His seminal work, "Use of a semi-automated, robotic radioimmunoassay to measure cAMP generated by activation of DP-, EP2-, and IP-prostaglandin receptors in human ocular and other cell types" (1998, 22 citations), introduced a high-throughput methodology that revolutionized the study of G protein-coupled receptor (GPCR) activity. By developing a robotic radioimmunoassay for cyclic AMP (cAMP) quantification, Xu enabled precise, reproducible measurement of receptor activation in human ocular cells—a critical advancement for understanding glaucoma and inflammatory eye diseases. This technical innovation bridged the gap between automated laboratory systems and complex cellular signaling, providing a foundation for later studies on prostaglandin analogs used in intraocular pressure management. Though his citation count reflects focused impact, Xu’s work remains a methodological cornerstone for researchers investigating GPCR-mediated pathways in sensory tissues. His contributions exemplify how rigorous assay development can accelerate drug discovery, particularly in ophthalmology, where prostaglandin receptors are key therapeutic targets.
Research Focus
Key Achievements
Top Papers
- 1