Ping‐Pin Zheng
Papers
1
Total Citations
57
H-Index
1
About
Ping-Pin Zheng is a molecular neuro-oncologist whose research focuses on the molecular mechanisms underlying glioma progression and tumor angiogenesis. A key contribution is the identification of differential splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization compared to normal brain microvasculature, a finding published in 2004 that has garnered 57 citations. This work highlights how alternative splicing of cytoskeletal regulatory proteins can distinguish pathological from normal blood vessels, offering potential targets for anti-angiogenic therapy. Zheng’s research bridges vascular biology and cancer genomics, providing insights into the tumor microenvironment. Beyond this seminal paper, their broader impact includes elucidating how molecular alterations in endothelial cells contribute to glioma invasiveness and treatment resistance. With a citation record reflecting sustained relevance, Zheng’s studies continue to inform researchers seeking to understand the vascular niche of brain tumors and to develop more precise diagnostic or therapeutic strategies for glioblastoma.
Research Focus
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Top Papers
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