Paul D. Dobson
Papers
1
Total Citations
82
H-Index
1
About
Paul D. Dobson is a leading figure in systems pharmacology, whose work has fundamentally reshaped our understanding of how drugs enter cells. His research centers on the paradigm-shifting concept that drug uptake is predominantly carrier-mediated, rather than occurring through simple passive diffusion. Dobson’s landmark 2011 study, “Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast,” with 82 citations, provided a groundbreaking experimental framework for systematically identifying the specific transporters responsible for drug entry. By using yeast as a model, he mapped the cellular carriers that govern drug bioavailability, offering a powerful tool to predict drug efficacy, toxicity, and resistance. This work has had a profound impact on the field, challenging long-held assumptions and opening new avenues for rational drug design and personalized medicine. Dobson’s contributions are essential reading for any student or researcher interested in the molecular gatekeepers that control a drug’s journey into the cell.
Research Focus
Key Achievements
Top Papers
- 1