Mohanram Gudipati
Papers
1
Total Citations
32
H-Index
1
About
Mohanram Gudipati is a molecular biologist whose research centers on the mechanisms of gene expression, particularly pre-mRNA splicing and RNA processing in eukaryotic cells. His most notable contribution is the development of a pioneering high-throughput reverse genetic screen in the budding yeast *Saccharomyces cerevisiae*, detailed in his highly cited 2012 paper. This work, which has garnered 32 citations, introduced a robust methodology that couples automated strain growth, robotic RNA isolation, and quantitative PCR to systematically probe the connections between pre-mRNA splicing and 5′ and 3′ end transcript determinants. By enabling genome-wide analysis of splicing efficiency, Gudipati’s approach has provided critical insights into the complex regulatory networks governing RNA maturation. His contributions have advanced the understanding of how splicing interfaces with other RNA processing steps, offering valuable tools for researchers studying gene regulation. Through this innovative work, Gudipati has established himself as a key figure in the field of RNA biology, demonstrating how high-throughput techniques can uncover novel genetic interactions and deepen our knowledge of fundamental cellular processes.
Research Focus
Key Achievements
Top Papers
- 1