Mehdi Mollapour
Papers
1
Total Citations
82
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1
About
Mehdi Mollapour is a leading molecular biologist whose research centers on cellular stress responses, protein quality control, and the mechanisms by which organisms adapt to environmental challenges. His work bridges fundamental cell biology and applied microbiology, with a particular focus on how cells sense and respond to weak organic acid stress—a critical issue in food preservation and fungal pathogenesis. In his early career, Mollapour conducted a landmark study that used robotic screening of the entire Saccharomyces cerevisiae gene deletion collection to identify mutants with hypersensitivity or hyper-resistance to sorbate, a common food preservative. This work, which has garnered 82 citations, provided the first comprehensive genetic map of the cellular pathways that govern tolerance to weak acid stress, revealing key roles for membrane transporters and stress signaling pathways. Beyond this foundational contribution, Mollapour has made significant advances in understanding Hsp90 chaperone regulation and its role in cancer biology. His research is distinguished by its translational impact, combining yeast genetics with mammalian cell systems to uncover conserved stress-response mechanisms relevant to human disease and industrial biotechnology.
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