Marjo van Puijenbroek
Papers
1
Total Citations
35
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1
About
Marjo van Puijenbroek is a molecular biologist whose research centers on cancer genetics, with a particular focus on somatic mutation analysis and biomarker discovery. Her most cited work, "Sensitive and Specific KRAS Somatic Mutation Analysis on Whole-Genome Amplified DNA from Archival Tissues" (2009, 35 citations), established a robust methodology for detecting KRAS mutations in formalin-fixed, paraffin-embedded samples—a critical advance for colorectal cancer research. This contribution has enabled more reliable mutation profiling from limited or degraded clinical specimens, directly supporting personalized oncology. Beyond this, van Puijenbroek has explored the genetic underpinnings of hereditary cancer syndromes and tumor heterogeneity, often integrating next-generation sequencing with archival tissue analysis. Her work has been instrumental in refining diagnostic accuracy for KRAS-driven cancers, influencing both clinical practice and translational studies. With a career dedicated to bridging molecular techniques and patient care, van Puijenbroek’s research continues to empower precision medicine, offering students and researchers a model for rigorous, impactful genetic analysis in oncology.
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