M. Dawn Teare

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About

M. Dawn Teare is a distinguished genetic epidemiologist whose research has significantly advanced the understanding of hereditary cancer susceptibility, particularly in prostate cancer. Her key contributions lie in identifying and characterizing high-risk genetic variants that predispose individuals to cancer development, with a focus on the complex interplay between genetic and environmental factors. Teare’s seminal work, including her highly cited 2000 paper "High risk genes predisposing to prostate cancer development—do they exist?" (25 citations), critically examined the evidence for rare, high-penetrance genes in prostate cancer, helping to shape the field’s approach to risk assessment and genetic counseling. Beyond this, she has made impactful contributions to the study of breast and ovarian cancer genetics, employing large-scale population studies and family-based analyses to uncover novel susceptibility loci. Her research has informed clinical guidelines for genetic testing and cancer prevention strategies. With a career marked by rigorous methodology and translational impact, Teare’s work continues to guide researchers and clinicians in the pursuit of personalized cancer risk prediction and early intervention.