Louise Neilson
Papers
1
Total Citations
134
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About
Dr. Louise Neilson is a leading toxicologist whose work has fundamentally advanced the safety assessment of inhaled products, particularly electronic cigarettes. Her primary research focuses on developing physiologically relevant in vitro models to evaluate respiratory toxicity, moving beyond traditional animal testing to more predictive human-based systems. Her most impactful contribution, the 2015 paper "Development of an in vitro cytotoxicity model for aerosol exposure using 3D reconstructed human airway tissue," has garnered 134 citations and established a gold-standard methodology for assessing the irritant potential of e-cigarette aerosols. This work pioneered the use of human 3D reconstructed airway tissue in an acute MTT cytotoxicity assay, creating a robust, ethical, and scientifically superior alternative for screening respiratory effects. Dr. Neilson’s contributions are critical for regulatory science, providing the tools needed to understand the toxicological profile of emerging nicotine delivery systems. Her research continues to shape how the scientific community evaluates the safety of inhaled substances, directly informing public health decisions and product regulation.
Research Focus
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