Jason DeBay
Papers
1
Total Citations
134
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1
About
Jason DeBay is a leading researcher in pulmonary toxicology and in vitro aerosol exposure science, with a focus on developing physiologically relevant models to assess respiratory health risks. His major contributions center on advancing alternative testing methods that reduce reliance on animal models while improving predictive accuracy for human airway responses. His most cited work, “Development of an in vitro cytotoxicity model for aerosol exposure using 3D reconstructed human airway tissue; application for assessment of e-cigarette aerosol” (2015, 134 citations), pioneered a novel acute MTT cytotoxicity assay using human 3D reconstructed airway tissue. This method enables precise evaluation of potential irritant effects from e-cigarette aerosols, addressing a critical gap in regulatory toxicology. DeBay’s research has significantly impacted the field by providing robust, standardized protocols for screening aerosolized substances, influencing both product safety assessments and public health guidelines. His work is widely recognized for bridging the gap between laboratory science and real-world exposure scenarios, making him a key figure in the ongoing debate over e-cigarette safety.
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