Lars Geffers
Papers
2
Total Citations
11
H-Index
2
About
Lars Geffers is a researcher specializing in developmental biology, bioinformatics, and metabolic gene expression, with a particular focus on understanding how metabolic pathways are regulated during embryonic development in mice. His work bridges the gap between biochemical pathway data and spatial gene expression analysis, making him a contributor to both computational and experimental biology. Among his most notable contributions is the development of METscout, a sophisticated MySQL relational database that integrates metabolic pathway information with three-dimensional gene expression patterns derived from robotic in situ hybridization in the E14.5 mouse embryo. This innovative tool, published in 2012 and accumulating 8 citations, provides researchers with a powerful resource for exploring the interplay between metabolism and gene regulation during development. Geffers has also made meaningful contributions to understanding cholesterol biosynthesis in embryonic development. His 2015 compendium systematically catalogued the expression patterns of cholesterol biosynthetic enzymes in the mouse embryo, shedding light on processes critical to membrane formation, hedgehog signaling, and steroid biogenesis. While his citation counts remain modest, his work provides foundational resources and datasets that support the broader developmental biology and systems biology communities.
Research Focus
Key Achievements
Top Papers
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