Kerui Xu

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About

Kerui Xu is a trailblazer in the field of single-cell proteomics, with a focus on developing ultra-sensitive sample processing workflows that push the boundaries of what is possible with limited biological material. Their most-cited work, "Benchtop-compatible sample processing workflow for proteome profiling of <100 mammalian cells" (2018, 58 citations), represents a landmark contribution to the field. This paper introduced a robust, accessible method for deep proteome profiling from as few as 100 cells, dramatically lowering the barrier for studying rare cell populations, such as stem cells or circulating tumor cells, without the need for specialized equipment. By enabling high-quality proteomic analysis from minimal starting material, Xu's work has empowered researchers to explore cellular heterogeneity and disease mechanisms at unprecedented resolution. This achievement has not only garnered significant attention, as reflected in its citation count, but has also inspired further innovations in single-cell proteomics. Xu’s dedication to making advanced proteomic tools benchtop-compatible underscores a commitment to democratizing cutting-edge technology, making their research invaluable for students and scientists seeking to unlock the proteome’s secrets from the scarcest of samples.